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New Insights Into How Major Weight-loss Drugs Work

Some of the most important weight-loss drugs work by enhancing the effect of the brain chemical serotonin. These include sibutramine (trade name Meridia) and fenfluramine, which was recalled after the combination with dexfenfluramine, called fen-phen, was linked to potentially fatal heart valve abnormalities.However, little has been known about the molecular mechanism by which serotonin suppresses appetite. [click link for full article]

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