Manhattan Pharmaceuticals Receives SwissMedic’s Approval To Commence Phase IIa Trial With OE, Its Oral Obesity Drug Candidate
Manhattan Pharmaceuticals, Inc. (Amex: MHA) today reported receipt of Swiss regulatory approval to commence its Phase IIa study with oral Oleoyl-estrone (OE), the company's drug candidate for the treatment of obesity. The single center, Phase IIa study is a randomized, double-blind,placebo-controlled, parallel group study designed to evaluate the safety,preliminary efficacy, and pharmacokinetics of two 14-day dosing cycles inobese adult subjects. [click link for full article]

No-Drug, Anti-Inflammatory Diet Yields Positive Clinical-Trial Results, Including Marked Improvement Of Metabolic Abnormalities And Rapid Weight Loss
Research about the benefits of ano-drug, anti-inflammatory, and non-special dietary supplements diet is tobe presented June 24-27 at the 2006 annual Endocrine Society's ScientificMeeting in Boston. The research's author is Frank K. Leung, M.D., a fellow of the AmericanCollege of Endocrinology, and a Harvard-trained, board-certified physicianwith more than 20 years of experience in weight-reduction management anddiabetes treatment. [click link for full article]

Mother dies days after having her stomach stapled
A mother died from complications four days after having a gastric bypass. Lynda Taylor, 33, opted for the risky surgery after failing to lose weight with dieting and anti-obesity drugs

Safer Anti-obesity Drugs May Stem From New Insight Into How Serotonin Reduces Appetite
A study led by a UT Southwestern Medical Center researcher sheds light on how the brain chemical serotonin, when spurred by diet drugs such as Fen-phen, works to curb appetite.That knowledge could aid in the design of safer anti-obesity drugs nearly a decade after Fen-phen was banned for causing harmful side effects. [click link for full article]

Suntory Finds That Oolong Tea-derived Polymerized Polyphenol Has Anti-obesity Effect
Suntory announced on May 22 that it has found a unique property of polymerized polyphenol derived from oolong tea. The company's R&D unit has confirmed that oolong-tea polymerized polyphenol demonstrates an anti-obesity effect in experiments with mice. Specifically, mice administered with a polymerized polyphenol-added high-fat and sugar diet showed the dose-dependent inhibition of weight and body fat. [click link for full article]