Search:

Yale Researchers Find New Molecular Target For Obesity

Mice bred without the enzyme MKP-1 are resistant to weight gain despite consuming high fat foods and eating more than control mice, according to a research study published online in Cell Metabolism. “The results from this study give us new molecular clues into how metabolic homeostasis is regulated and the possibility of new therapeutic avenues to specifically combat obesity,” said the senior author, Anton Bennett, associate professor,Department of Pharmacology. [click link for full article]

More: continued here

Leave a Reply

Powered by Article Dashboard

Related News


  • Obesity Levels In US Are Grossly Underestimated
    The prevalence of obesity in the U.S. states has been greatly underestimated. Researchers at the Harvard School of Public Health (HSPH) analyzed data from health surveys, which are used to estimate obesity levels in states. Because people tend to provide incorrect information about their weight and height, especially in telephone surveys, the researchers concluded that estimates of obesity in individual states have been too low, by more than 50%. [click link for full article]


  • MCP-1: The Missing Link Between Obesity And Insulin Resistance
    Individuals diagnosed with metabolic syndrome often have excessive fatty tissue in and around their abdomen, high cholesterol, elevated blood pressure, and an inability to utilize insulin or blood sugar (insulin resistance) - symptoms that put them at high risk of coronary heart disease and stroke. The molecular mechanisms that link obesity and insulin resistance are the subject of intense investigation and are not completely understood. [click link for full article]


  • New Insights Into How Major Weight-loss Drugs Work
    Some of the most important weight-loss drugs work by enhancing the effect of the brain chemical serotonin. These include sibutramine (trade name Meridia) and fenfluramine, which was recalled after the combination with dexfenfluramine, called fen-phen, was linked to potentially fatal heart valve abnormalities.However, little has been known about the molecular mechanism by which serotonin suppresses appetite. [click link for full article]


  • Workout of the Week - No Equipment Travel Workout
    When I go on vacation, my workouts tend to be easy to the point of not actually existing. Like many travelers, I find it difficult to exercise without my...


  • Study Links Obesity To Liver Failure
    Researchers have found that obesity can put patients with acute liver failure at increased risk of mortality and other major complications, according to a new study presented today at Digestive Disease Week? 2006 (DDW). DDW is the largest international gathering of physicians and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. [click link for full article]